Steroid 5alpha-reductase inhibitory activity and hair
regrowth effects of an extract from Boehmeria nipononivea.
Shimizu K, Kondo R, Sakai K, Shoyama Y, Sato H, Ueno T.
Department of Forest Products, Faculty of Agriculture, Kyushu University,
The acetone extract of Boehmeria nipononivea showed both potent 5alpha-reductase
inhibitory activity and hair regrowth promotion effects on mice.
5alpha-Reductase inhibitory activity-guided fractionation led to six active
fatty acids: alpha-linolenic, linoleic, palmitic, elaidic, oleic and stearic
acids. The extract of B. nipononivea, and alphalinolenic, elaidic and stearic
acids exhibited a hair regrowth effect.